BDBM50031649 2-{3-(4-benzyloxy)-2-[(dimethylamino)methyl]-3-oxopropyl}hydrazinecarboxamide hydrochloride::CHEMBL541307

SMILES CN(C)CC(CNNC(N)=O)C(=O)c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=PAMFLGPSTJPJQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031649   

TargetEpidermal growth factor receptor(Human)
Ciba

Curated by ChEMBL
LigandPNGBDBM50031649(2-{3-(4-benzyloxy)-2-[(dimethylamino)methyl]-3-oxo...)
Affinity DataIC50: 3.90E+3nMAssay Description:In vitro inhibition of the Epidermal growth factor receptor activity in A431 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ciba

Curated by ChEMBL
LigandPNGBDBM50031649(2-{3-(4-benzyloxy)-2-[(dimethylamino)methyl]-3-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of the v-abl tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
LigandPNGBDBM50031649(2-{3-(4-benzyloxy)-2-[(dimethylamino)methyl]-3-oxo...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of the c-src tyrosine kinase activity in A431 membranes using angiotensin II as phosphate acceptor as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed