BDBM50031737 CHEMBL3360840

SMILES Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1

InChI Key InChIKey=BYWJAVQGRJEEHH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031737   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031737(CHEMBL3360840)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of JAK1 in human whole blood assessed as inhibition of IL-6-induced pSTAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031737(CHEMBL3360840)
Affinity DataIC50:  307nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031737(CHEMBL3360840)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of JAK2 in human whole blood assessed as inhibition of GM-CSF-induced pSTAT5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed