BDBM50032719 CHEMBL3354695
SMILES CC1(C)CN(CCO1)c1ccc2Oc3ccc(cc3[C@@]3(COC(N)=N3)c2c1)-c1cncnc1
InChI Key InChIKey=QPHLVXZLURTAQR-VWLOTQADSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50032719
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ERG expressing HEK293 cells by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE1 (unknown origin) assessed as enhancement of fluorescence intensityMore data for this Ligand-Target Pair