BDBM50032739 CHEMBL3354720

SMILES NC1=N[C@@]2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(N3CC[C@H](F)C3)cc12

InChI Key InChIKey=QACXZFDNMSEDFG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50032739   

TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50032739BDBM50032739(CHEMBL3354720)
Affinity DataIC50: 7nMAssay Description:Inhibition of BACE1 in HEK293T cells expressing APPswedish mutant assessed as inhibition of amyloid beta 40 production by sandwich ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50032739BDBM50032739(CHEMBL3354720)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human ERG expressing HEK293 cells by [3H]dofetilide binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed