BDBM50032803 2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1-(3-morpholin-4-yl-ureidocarbonyl)-butyl]-4-phenyl-butyramide::CHEMBL108746

SMILES CC(C)CC(NC(=O)C(CCc1ccccc1)N=CCS(=O)(=O)c1ccccc1)C(=O)NC(=O)NN1CCOCC1

InChI Key InChIKey=TVUDUONIRJXXCP-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50032803   

TargetCathepsin S(Human)
Khepri Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032803(2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1...)
Affinity DataKi:  5.90nMAssay Description:Compound is evaluated for inhibitory potency against cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Khepri Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032803(2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1...)
Affinity DataKi:  220nMAssay Description:Compound is evaluated for inhibitory potency against CruzaineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Khepri Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032803(2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1...)
Affinity DataKi:  230nMAssay Description:Compound is evaluated for inhibitory potency against cathepsin O2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Khepri Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032803(2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1...)
Affinity DataKi:  720nMAssay Description:Compound is evaluated for inhibitory potency against cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Khepri Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032803(2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1...)
Affinity DataKi:  3.90E+4nMAssay Description:Compound is evaluated for inhibitory potency against cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed