BDBM50033909 CHEMBL6590::N-Furan-3-ylmethyl-4-[(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzamide

SMILES C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NCc2ccoc2)cc1

InChI Key InChIKey=SJCOVOXWSZPSOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033909   

TargetThymidylate synthase(Mouse)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033909BDBM50033909(N-Furan-3-ylmethyl-4-[(2-methyl-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed