BDBM50033910 4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-N-(3-nitro-benzyl)-benzamide::CHEMBL268453

SMILES C#CCN(Cc1cc2c(=O)[nH]c(C)nc2cc1C)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)c(F)c1

InChI Key InChIKey=QDONLEJFIXLJSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50033910   

TargetThymidylate synthase(Mouse)
Zeneca Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033910BDBM50033910(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory activity against thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Mouse)
Zeneca Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033910BDBM50033910(4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50: 44nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed