BDBM50033925 3-({4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-methyl)-benzoic acid::CHEMBL6850

SMILES C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NCc2cccc(C(=O)O)c2)cc1

InChI Key InChIKey=IWTLSNQWFCQMPR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033925   

TargetThymidylate synthase(Mouse)
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033925BDBM50033925(3-({4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-yl...)
Affinity DataIC50: 270nMAssay Description:Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed