BDBM50034020 (S)-9-Aminomethyl-4-ethyl-4-hydroxy-11-methyl-8-oxy-1,12-dihydro-4H-2-oxa-6,8,12a-triaza-dibenzo[b,h]fluorene-3,13-dione::CHEMBL275134

SMILES CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4c[n+]([O-])c(CN)cc4c(C)c3Cn1c2=O

InChI Key InChIKey=RZCQWMNDDPDWBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50034020   

TargetDNA topoisomerase 1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50034020((S)-9-Aminomethyl-4-ethyl-4-hydroxy-11-methyl-8-ox...)
Affinity DataIC50: 190nMAssay Description:Minimum concentration that produced 50% fragmentation of DNA was measured in the presence of excess calf thymus topoisomerase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed