BDBM50034406 22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-2,16-diol::CHEMBL282107

SMILES Oc1ccc2c3c1O[C@H]1c4c(c5ccccc5n4Cc4ccc(N=C=S)cc4)C[C@@]4(O)C(C2)N(CC2CC2)CCC314

InChI Key InChIKey=OXVIDGHUFWUYCY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50034406   

TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034406BDBM50034406(22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-1...)
Affinity DataKi:  5nMAssay Description:Tested for binding affinity against delta2 opioid receptor using [3H]DSLET as a radioligand in the guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034406BDBM50034406(22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-1...)
Affinity DataKi:  5.30nMAssay Description:Tested for binding affinity against delta1 opioid receptor using [3H]-DPDPE as a radioligand in the guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034406BDBM50034406(22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-1...)
Affinity DataKi:  245nMAssay Description:Tested for binding affinity against Opioid receptor kappa 1 using [3H]U-69593 as a radioligand in the guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50034406BDBM50034406(22-cyclopropylmethyl-11-(4-isothiocyanatobenzyl)-1...)
Affinity DataKi:  289nMAssay Description:Tested for binding affinity against mu opioid receptor using [3H]DAMGO as a radioligand in the guinea pig brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed