BDBM50034854 (2R,4S)-5-Biphenyl-4-yl-4-(4-carboxy-butyrylamino)-2-methyl-pentanoic acid::CHEMBL295037::US10123984, Compound 21e

SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCCC(O)=O)C(O)=O

InChI Key InChIKey=XYPZEWFZPBNHRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034854   

TargetNeprilysin(Human)
Theravance Biopharma R&D Ip

US Patent
LigandPNGBDBM50034854((2R,4S)-5-Biphenyl-4-yl-4-(4-carboxy-butyrylamino)...)
Affinity DataIC50: 90nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034854((2R,4S)-5-Biphenyl-4-yl-4-(4-carboxy-butyrylamino)...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibition of rat neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed