BDBM50034866 2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pentanoic acid::CHEMBL47289

SMILES OC(=O)CCNC(=O)C(CC(Cc1ccccc1)C(O)=O)Cc1ccccc1

InChI Key InChIKey=JUUGRNXBMBREMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034866   

TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034866(2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 18nMAssay Description:Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2012
Entry Details Article
PubMed
TargetNeprilysin(Rabbit)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50034866(2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 18nMAssay Description:Tested for inhibitory potency against neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeprilysin(Rat)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50034866(2-Benzyl-4-(2-carboxy-ethylcarbamoyl)-5-phenyl-pen...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibition of rat neutral endopeptidase by using GAAP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed