BDBM50034912 (S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide::Ac-DPhe-Arg-Trp-NH2::CHEMBL432895

SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key InChIKey=LUCUFURZWPZEOH-KMDXXIMOSA-N

Data  4 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034912   

TargetMelanocortin receptor 3(Human)
University of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 3 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at mouse MC1 receptor expressed in HEK-293 cells assessed as cAMP response measured after 2 hrs incubation by cAMP Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Human)
University of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 5 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataEC50:  2.32E+3nMAssay Description:Functional activity at the mouse melanocortin 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Human)
University of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50:  2.08E+3nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 4 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataEC50:  4.54E+3nMAssay Description:Functional activity at the mouse melanocortin 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataEC50:  1.66E+3nMAssay Description:Functional activity at the mouse melanocortin 5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Michigan Medical Center

Curated by ChEMBL
LigandPNGBDBM50034912((S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]NDP-MSH from Melanocortin 1 receptor at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed