BDBM50035301 CHEMBL71899::Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine

SMILES CCCN(CCC)C1CCc2ccc3[nH]cc(CC(F)(F)F)c3c2C1

InChI Key InChIKey=LKUMKJQSYINUSG-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50035301   

Target5-hydroxytryptamine receptor 1A(Rat)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  18nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor from CHO-K1 cells, using [3H]8-OH-DPAT as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  54nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor alpha expressed in CHO-K1 cells, using [3H]-5-HT as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  86nMAssay Description:Binding affinity against Dopamine receptor D2 expressed in CHO-K1 cells, using [3H]U-86170 as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  134nMAssay Description:The compound was tested in vitro for binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]spiperone as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  182nMAssay Description:Displacement of the radioligand [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  409nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta expressed in CHO-K1 cells, using [3H]5-HT as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
GöTeborg University

Curated by ChEMBL
LigandPNGBDBM50035301(Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrah...)
Affinity DataKi:  796nMAssay Description:Displacement of the radioligand [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed