BDBM50035345 CHEMBL71145::Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-(2-thiophen-2-yl-ethyl)-amine

SMILES CCCN(CCc1cccs1)C1CCc2ccc3[nH]ccc3c2C1

InChI Key InChIKey=OLGRDJBZDHQHOJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035345   

Target5-hydroxytryptamine receptor 1A(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50035345(Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-...)
Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1A receptor expressed in CHO cells, by using [3H]8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50035345(Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-...)
Affinity DataKi:  5.5nMAssay Description:In vitro binding affinity against cloned mammalian Dopamine receptor D3 expressed in CHO cells by, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50035345(Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Upjohn Laboratories

Curated by ChEMBL
LigandPNGBDBM50035345(Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-...)
Affinity DataKi:  13nMAssay Description:In vitro binding affinity against cloned mammalian 5-hydroxytryptamine 1D receptor alpha expressed in CHO cells, by using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed