BDBM50035588 CHEMBL3357134

SMILES COC(=O)Nc1cc(NC(=O)c2c[nH]c3ccccc3c2=O)ccc1C(C)(C)C

InChI Key InChIKey=AVVSAXDYLAXTFZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035588   

TargetCystic fibrosis transmembrane conductance regulator(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50035588(CHEMBL3357134)
Affinity DataEC50:  3.50E+3nMAssay Description:Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed