BDBM50035813 CHEMBL3359920

SMILES C[C@@]1(N)CC[C@@H](Nc2c(cnn3cccc23)C(N)=O)C1(C)C

InChI Key InChIKey=CLYUZZLJBLEOOA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035813   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035813(CHEMBL3359920)
Affinity DataIC50: 32nMAssay Description:Inhibition of JAK3 (unknown origin) by filter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035813(CHEMBL3359920)
Affinity DataIC50: 52nMAssay Description:Inhibition of TYK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035813(CHEMBL3359920)
Affinity DataIC50: 71nMAssay Description:Inhibition of JAK1 (unknown origin) bycaliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035813(CHEMBL3359920)
Affinity DataIC50: 280nMAssay Description:Inhibition of JAK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed