BDBM50035846 CHEMBL3359912

SMILES CC1(C)[C@@H](O)CC[C@H]1Nc1c(cnn2cccc12)C(N)=O

InChI Key InChIKey=NQMVPZBPGADIQN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035846   

TargetTyrosine-protein kinase JAK3(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50: 16nMAssay Description:Inhibition of JAK3 (unknown origin) by filter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50: 62nMAssay Description:Inhibition of JAK1 (unknown origin) bycaliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50: 79nMAssay Description:Inhibition of TYK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50035846(CHEMBL3359912)
Affinity DataIC50: 130nMAssay Description:Inhibition of JAK2 (unknown origin) by caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed