BDBM50035986 2-(3-Difluoromethyl-phenylamino)-1,9-dihydro-purin-6-one::CHEMBL152257

SMILES FC(F)c1cccc(Nc2nc3nc[nH]c3c(=O)[nH]2)c1

InChI Key InChIKey=JRLITVMWEMTPRW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035986   

TargetThymidine kinase(HHV-1)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50035986(2-(3-Difluoromethyl-phenylamino)-1,9-dihydro-purin...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of HSV-1 thymidine kinase, 1 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidine kinase(HHV-2)
University of Massachusetts Medical School

Curated by ChEMBL
LigandPNGBDBM50035986(2-(3-Difluoromethyl-phenylamino)-1,9-dihydro-purin...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of HSV-2 thymidine kinase, 2 uM [3H]thymidine and ATP as phosphate donorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed