BDBM50037528 (S)-4-(2,5-Dimethyl-thiazole-4-sulfonyl)-1-[(2S,4R)-2-hydroxy-4-((R)-(R)-2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentyl]-piperazine-2-carboxylic acid tert-butylamide::CHEMBL116628

SMILES Cc1nc(c(C)s1)S(=O)(=O)N1CCN(C[C@@H](O)C[C@@H](Cc2ccccc2)C(=O)NC2[C@H](O)Cc3ccccc23)[C@@H](C1)C(=O)NC(C)(C)C

InChI Key InChIKey=AZMMWXVEVKAJAZ-ROFASSETSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037528   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50037528((S)-4-(2,5-Dimethyl-thiazole-4-sulfonyl)-1-[(2S,4R...)
Affinity DataIC50:  0.160nMAssay Description:Evaluated for the inhibition of HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed