BDBM50037557 2-{[1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-pentanedioic acid 5-amide 1-{[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide}::CHEMBL429731
SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=HWYCFZUSOBOBIN-AQJXLSMYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50037557
Affinity DataKi: 0.0200nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFFMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]EYE from human NPFF2 receptor expressed in CHO cell membranes after 1 hr by liquid scintillation spectrophotometric countingMore data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Agonist activity at NPFF2R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 275nMAssay Description:Agonist activity at NPFF1R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 274nMAssay Description:Agonist activity at NPFF1R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:Agonist activity at NPFF2R (unknown origin) expressed in HEK293-A cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated fo...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Binding affinity to human NPFFR2 expressed in green monkey COS-7 cell membranes by [125I]-1DMeNPFF radioligand based saturation binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity to human NPFFR1 expressed in green monkey COS-7 cell membranes by [125I]-1DMeNPFF radioligand based saturation binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 158nMAssay Description:Agonist activity at NPFF1 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at NPFF2 receptor (unknown origin) expressed in HEK293A cells assessed as inhibition of forskolin-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
Affinity DataKd: 0.210nMAssay Description:Binding affinity to human NPFFR2More data for this Ligand-Target Pair