BDBM50038642 22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13.9.1.01,13.02,21.03,11.05,10.019,25]pentacosa-3(11),5(10),6,8,15,17,19(25)-heptaen-16-ol::CHEMBL291973

SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2Cc2c([nH]c4ccccc24)[C@H]3[C@H]1C5

InChI Key InChIKey=TVTQHEAJUSXWSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50038642   

TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038642BDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50: 920nMAssay Description:Antagonist activity against mu-opioid receptor in guinea pig ileum in the presence of morphineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038642BDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50: 990nMAssay Description:Antagonist activity against kappa-opioid receptor in guinea pig ileum in the presence of ethylketazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038642BDBM50038642(22-methyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13....)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed