BDBM50040360 8-Amino-1,3-bis-cyclopropylmethyl-7-(4-nitro-benzenesulfonyl)-3,7-dihydro-purine-2,6-dione::CHEMBL144656

SMILES Nc1nc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c2n1S(=O)(=O)c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=YAZXYHMZIMSXGE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040360   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL

LigandBDBM50040360(8-Amino-1,3-bis-cyclopropylmethyl-7-(4-nitro-benze...)Copy SMILESCopy InChI

Affinity DataIC50:  3.80E+4nMAssay Description:Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
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