BDBM50040590 (R)-2-[(S)-1-(Benzyl-methyl-carbamoyl)-3-methyl-butylamino]-4-(1,3-dioxo-1,3-dihydro-benzo[f]isoindol-2-yl)-butyric acid::CHEMBL162072

SMILES CC(C)C[C@H](N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O)C(=O)N(C)Cc1ccccc1

InChI Key InChIKey=PCKJJBIMKAITOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040590   

TargetInterstitial collagenase(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040590((R)-2-[(S)-1-(Benzyl-methyl-carbamoyl)-3-methyl-bu...)
Affinity DataIC50: 37nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040590((R)-2-[(S)-1-(Benzyl-methyl-carbamoyl)-3-methyl-bu...)
Affinity DataIC50: 57nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040590((R)-2-[(S)-1-(Benzyl-methyl-carbamoyl)-3-methyl-bu...)
Affinity DataIC50: 1.16E+3nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed