BDBM50040616 (R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl)-2-[(S)-3-methyl-1-((S)-3-methyl-1-methylcarbamoyl-butylcarbamoyl)-butylamino]-butyric acid::CHEMBL161536

SMILES CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O

InChI Key InChIKey=XRAGTWOVABKXJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040616   

TargetMatrix metalloproteinase-9(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040616((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 11nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040616((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 49nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040616((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50: 1.30E+3nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed