BDBM50040809 CHEMBL3353209::US9169260, 320

SMILES Cc1ccc(nc1)-n1nc(cc1NC(=O)c1cnn2cccnc12)N1CCN(CC1)C1CCC1

InChI Key InChIKey=AITFTCYSYZAHBT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040809   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL

LigandBDBM50040809(CHEMBL3353209 | US9169260, 320)Copy SMILESCopy InChI

Affinity DataIC50: <100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL

LigandBDBM50040809(CHEMBL3353209 | US9169260, 320)Copy SMILESCopy InChI

Affinity DataIC50: <100nMpH: 7.2Assay Description:The kinase activity of IRAK-4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phos...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent

Copy BDB DOI
Copy reaction URL