BDBM50040874 CHEMBL3353187

SMILES Cl.Cc1cc(ccn1)-c1nc(co1)C(=O)Nc1cn(nc1C(N)=O)C1CCOCC1

InChI Key InChIKey=JANBIXNDYNRYQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040874   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040874(CHEMBL3353187)
Affinity DataIC50:  21nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterleukin-1 receptor-associated kinase 1(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50040874(CHEMBL3353187)
Affinity DataIC50:  800nMAssay Description:Inhibition of human IRAK1 using biotinylated FGLARFSRFAGSSPSQSSMVARTQTVRGT peptide as substrate incubated for 1 hr in presence of ATP by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed

TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040874(CHEMBL3353187)
Affinity DataIC50:  20nMAssay Description:Inhibition of human IRAK4 using biotinylated FGLARFSRFAGSSPSQSSMVARTQTVRGT peptide as substrate incubated for 1 hr in presence of ATP by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed