BDBM50041051 2-[3-(4-Hydroxy-3-methoxy-phenyl)-2-mercaptomethyl-butyrylamino]-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL11344

SMILES COc1cc(ccc1O)C(C)C(CS)C(=O)NC(Cc1ccc(O)cc1)C(O)=O

InChI Key InChIKey=JPPOVCVCMLFFCR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041051   

TargetNeprilysin(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50041051(2-[3-(4-Hydroxy-3-methoxy-phenyl)-2-mercaptomethyl...)
Affinity DataIC50: 65nMAssay Description:In vivo inhibitory potency against neutral endopeptidase by displacement of [3H]HACBOGly binding in mouse kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Mouse)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50041051(2-[3-(4-Hydroxy-3-methoxy-phenyl)-2-mercaptomethyl...)
Affinity DataIC50: 14nMAssay Description:Inhibitory potency against angiotensin converting enzyme by displacement of [3H]trandolaprilate binding in mouse lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed