BDBM50041581 1,3,5-Trimethyl-6-((E)-styryl)-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL39898

SMILES Cn1c(\C=C\c2ccccc2)cc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=CPTGMMDIEVVMQA-MDZDMXLPSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50041581   

TargetAdenosine receptor A2a(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50041581(1,3,5-Trimethyl-6-((E)-styryl)-1,5-dihydro-pyrrolo...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
Eberhard-Karls-UniversitäT TüBingen

Curated by ChEMBL
LigandPNGBDBM50041581(1,3,5-Trimethyl-6-((E)-styryl)-1,5-dihydro-pyrrolo...)
Affinity DataKi:  2.60E+3nMAssay Description:Binding affinity to A1 adenosine receptor from rat cortical membrane in presence of [3H]-R-(phenylisopropyl)-adenosineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
University of Parma

Curated by ChEMBL
LigandPNGBDBM50041581(1,3,5-Trimethyl-6-((E)-styryl)-1,5-dihydro-pyrrolo...)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of human MAOB after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed