BDBM50041967 Benzyl-{4-oxo-2-propyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-carbamic acid isobutyl ester::Benzyl-{4-oxo-2-propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-carbamic acid isobutyl ester::CHEMBL108981

SMILES CCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(Cc1ccccc1)C(=O)OCC(C)C

InChI Key InChIKey=BLKGBLIWUFMXLD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041967   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50041967(Benzyl-{4-oxo-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from type 1 Angiotensin II receptor of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041967(Benzyl-{4-oxo-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125 I]Sar1Ile8-AII from AT2 receptor of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50041967(Benzyl-{4-oxo-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  0.600nMAssay Description:Binding affinity against Angiotensin II receptor type 2 from rat mid brain using [125I]-Sar1-Ile8-Ang II without BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50041967(Benzyl-{4-oxo-2-propyl-3-[2'-(1H-tetrazol-5-yl)-bi...)
Affinity DataIC50:  4.90nMAssay Description:Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed