BDBM50042280 CHEMBL3360734

SMILES Cc1ccc2oc(=O)c(cc2c1)-c1cccc(N)c1

InChI Key InChIKey=LGZDIVLUIURHFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042280   

TargetAmine oxidase [flavin-containing] B(Human)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50042280(CHEMBL3360734)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells using p-tyramine substrate assessed as reduction in H2O2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidad De Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50042280(CHEMBL3360734)
Affinity DataIC50: 60nMAssay Description:Inhibition of human MAO-B using p-tyramine as substrate incubated for 10 mins by Amplex Red reagent and horseradish peroxidase based fluorescence ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed