BDBM50042355 5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino]-methyl}-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL82924

SMILES CN(Cc1cnc2nc(N)nc(N)c2c1C)c1cc(Cl)c(Cl)c(Cl)c1

InChI Key InChIKey=SSRULYXLEIMTOP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50042355   

TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 36nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 36.3nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from rat liver (rl)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductases (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 38.1nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Toxoplasma gondii(tg)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 105nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii(pc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50042355(5-Methyl-6-{[methyl-(3,4,5-trichloro-phenyl)-amino...)
Affinity DataIC50: 105nMAssay Description:Inhibitory concentration against Pneumocystis carinii dihydrofolate reductases (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed