BDBM50042361 CHEMBL324839::{3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)-phenoxy]-propyl}-phosphonic acid

SMILES Nc1nc2c(ncn2Cc2ccccc2OCCCP(=O)(O)O)c(=O)[nH]1

InChI Key InChIKey=OJNSVMIPSNMEFV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50042361   

TargetPurine nucleoside phosphorylase(Human)
Burroughs Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042361BDBM50042361({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of purine nucleoside phosphorylase of human erythrocytes in xanthine oxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Burroughs Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042361BDBM50042361({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Burroughs Wellcome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042361BDBM50042361({3-[2-(2-Amino-6-oxo-1,6-dihydro-purin-9-ylmethyl)...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed