BDBM50042395 CHEMBL117336::[3-Methyl-1-(1-phenethylaminooxalyl-propylcarbamoyl)-butyl]-carbamic acid benzyl ester
SMILES CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCc1ccccc1
InChI Key InChIKey=QDIFXVWJRNFSAW-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50042395
Affinity DataKi: 22nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
Affinity DataKi: 22nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of the cysteine protease human Calpain 1More data for this Ligand-Target Pair
TargetCalpain small subunit 1/1 catalytic subunit(Human)
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+4nMpH: 6.0Assay Description:Inhibitory activity of alpha-ketoesters towards papain at pH 6.0More data for this Ligand-Target Pair