BDBM50042408 CHEMBL419590::[1-(1-Benzyl-2-benzylcarbamoyl-2-oxo-ethylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester

SMILES CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCc1ccccc1

InChI Key InChIKey=OMRMJPJSXPRGHA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042408   

TargetCalpain-2 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  46nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  46nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bovine)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  4.60E+3nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042408(CHEMBL419590 | [1-(1-Benzyl-2-benzylcarbamoyl-2-ox...)
Affinity DataKi:  4.60E+3nMAssay Description:Compound was evaluated for the inhibition of Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed