BDBM50042410 3-[2-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-4-methyl-pentanoylamino]-2-oxo-4-phenyl-butyric acid ethyl ester::CHEMBL3142933

SMILES CCOC(=O)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=VGQDAFRILWAFTH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042410   

TargetCalpain small subunit 1/1 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042410(3-[2-(2-Benzyloxycarbonylamino-4-methyl-pentanoyla...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibitory activity of alpha-keto esters towards calpain 1 at pH 8.0.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-2 catalytic subunit(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042410(3-[2-(2-Benzyloxycarbonylamino-4-methyl-pentanoyla...)
Affinity DataKi:  1.90E+3nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPapain(Papaya)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042410(3-[2-(2-Benzyloxycarbonylamino-4-methyl-pentanoyla...)
Affinity DataKi:  1.50E+4nMpH: 6.0Assay Description:Inhibitory activity of alpha-ketoesters towards papain at pH 6.0More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50042410(3-[2-(2-Benzyloxycarbonylamino-4-methyl-pentanoyla...)
Affinity DataKi:  4.20E+4nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed