BDBM50042496 CHEMBL119499::N-[(2,2-dimethyl-6-phenyoxy-2H-chromen-3-yl)methyl]-N-hydroxyurea

SMILES CC1(C)Oc2ccc(Oc3ccccc3)cc2C=C1CN(O)C(N)=O

InChI Key InChIKey=MQVRRZMLCHJUOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042496   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042496(CHEMBL119499 | N-[(2,2-dimethyl-6-phenyoxy-2H-chro...)
Affinity DataIC50:  440nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50042496(CHEMBL119499 | N-[(2,2-dimethyl-6-phenyoxy-2H-chro...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase by reduction of 5-hydroxyeicosatetraenoic acid (5-HETE) formed in guinea pig polymorphonuclear le...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed