BDBM50042863 CHEMBL3354513

SMILES Fc1cccc(F)c1-c1nc(cs1)C(=O)Nc1cnccc1OC1CCNCC1

InChI Key InChIKey=FTEJBTVRJIRRSV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50042863   

TargetSerine/threonine-protein kinase pim-3(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of wild type full length N-terminal his-tagged PIM1 (1 to 313 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 11nMAssay Description:Inhibition of wild type N-terminal GST-tagged PIM3 (1 to 326 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 18nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042863(CHEMBL3354513)
Affinity DataIC50: 113nMAssay Description:Inhibition of N-terminal GST-tagged PIM2 (1 to 311 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed