BDBM50042867 CHEMBL3354517

SMILES O[C@H]1CC[C@@H](CC1)Oc1ccncc1NC(=O)c1csc(n1)-c1c(F)cccc1F

InChI Key InChIKey=MQUXRVLSWBLTHR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042867   

TargetSerine/threonine-protein kinase pim-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50: 1nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of wild type full length N-terminal his-tagged PIM1 (1 to 313 residues) (unknown origin) expressed in Sf21 insect cells using STK3 as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50042867(CHEMBL3354517)
Affinity DataIC50: 36nMAssay Description:Inhibition of PIM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2016
Entry Details Article
PubMed