BDBM50043210 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione::CHEMBL340019

SMILES CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)[C@@H](C)Cc1ccccc1

InChI Key InChIKey=MFDOIDPESZOBLK-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043210   

TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  60.7nMAssay Description:Binding affinity towards adenosine A1 receptor was determined using radioligand [3H]CHA in whole rat brain membranes at 25 degree CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Marion Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  61nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50043210(8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihyd...)
Affinity DataKi:  848nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2012
Entry Details Article
PubMed