BDBM50043380 CHEMBL3355065
SMILES CNc1cc2ccc(cc2cn1)C#CCOc1ccc(CN2CCNCC2)c(c1)C(F)(F)F
InChI Key InChIKey=FTDWSWREBGYXDZ-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50043380
Affinity DataIC50: 19nMAssay Description:Inhibition of MELK (unknown origin) using KKLNRTLSFAEPG substrate by Millipore/scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of MELK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of Flt1 (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Astex Pharmaceuticals
Curated by ChEMBL
Astex Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Flt4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Yes1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of DDR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Flt3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of NTRK2 (unknown origin)More data for this Ligand-Target Pair