BDBM50043393 2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmethyl)-amino]-naphthalene-1-carbonyl}-amino)-pentanedioic acid::CHEMBL132142

SMILES Nc1nc(N)c2cc(CNc3ccc(C(=O)NC(CCC(O)=O)C(O)=O)c4ccccc34)cnc2n1

InChI Key InChIKey=ZWIUDBCRBSGGNP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50043393   

TargetDihydrofolate reductase(Mouse)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50043393(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataKi:  0.00365nMAssay Description:Inhibitory activity of Dihydrofolate reductase in L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Rat)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50043393(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataIC50:  0.00160nMAssay Description:Tested for inhibition against Dihydrofolate reductase from T. gondiiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50043393(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataIC50:  0.000530nMAssay Description:Tested for inhibition against Dihydrofolate reductase from P. cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDihydrofolate reductase(Pneumocystis carinii)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50043393(2-({4-[(2,4-Diamino-pyrido[2,3-d]pyrimidin-6-ylmet...)
Affinity DataIC50:  0.000530nMAssay Description:Tested for inhibition against Dihydrofolate reductase from P. cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed