BDBM500435 7-[[5-[(3S)-3- amino-1-piperipyl]-2- pyridyl]amino]- 4-(l-methylpyrrolo [2,3-b]pyridin- 4-yl)isoindolin-1-one::US11021481, Compound I-94::US11078201, Compound I-94::US11548890, Compound I-94

SMILES Cn1ccc2c(ccnc12)-c1ccc(Nc2ccc(cn2)N2CCC[C@H](N)C2)c2C(=O)NCc12

InChI Key InChIKey=NTVAHVZNPQNCRS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 500435   

LigandPNGBDBM500435(US11021481, Compound I-94 | 7-[[5-[(3S)-3- amino-1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent

LigandPNGBDBM500435(US11021481, Compound I-94 | 7-[[5-[(3S)-3- amino-1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent

LigandPNGBDBM500435(US11021481, Compound I-94 | 7-[[5-[(3S)-3- amino-1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM500435(US11021481, Compound I-94 | 7-[[5-[(3S)-3- amino-1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

LigandPNGBDBM500435(US11021481, Compound I-94 | 7-[[5-[(3S)-3- amino-1...)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent