BDBM50045603 CHEMBL3314316::US9540323, 161::US9540323, example 161
SMILES CC1(C)CN(c2c1c(c(F)cc2O)-c1cc(F)nc(F)c1)c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
InChI Key InChIKey=AOVDOABPZSHYNE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50045603
Affinity DataKi: 6.60nM ΔG°: -11.2kcal/molepH: 7.4 T: 2°CAssay Description:A SPA membrane binding assay was used to identify inhibitors of [33P] 2MeS-ADP binding to cloned human P2Y1 receptors (The P2Y1 receptor membranes we...More data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Antagonist activity at P2Y1 receptor in washed human platelets assessed as 1 uM 2-methylthio-ADP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Antagonist activity at P2Y1 receptor in platelet-enriched human plasma assessed as 10 uM ADP-induced platelet aggregation preincubated for 1 min foll...More data for this Ligand-Target Pair