BDBM50045883 CHEMBL99808::N,N-Dihexyl-2-(6H-isoindolo[2,1-a]indol-11-yl)-acetamide

SMILES CCCCCCN(CCCCCC)C(=O)Cc1c2-c3ccccc3Cn2c2ccccc12

InChI Key InChIKey=TZWKIWBBKZFDIF-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50045883   

TargetTranslocator protein(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataKi:  7.70nMAssay Description:Binding affinity against mitochondrial DBI complex (peripheral benzodiazepine receptor) using primary cultures of glial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCannabinoid receptor 1(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity, measured by displacement [3H]-CP-55,940 from cannabinoid receptor (CB1) in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-1/Beta-2/Beta-3 adrenergic receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [3H]naxolone binding to opiate receptors in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]ketanserin from serotonin receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGastrin/cholecystokinin type B receptor(Rat)
Mayo Foundation

Curated by ChEMBL
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]L-365,260 from cholecystokinin receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Tested for inhibitory activity by measuring its ability to displace [3H]3-PPP from opiate receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed