BDBM50046232 2-Amino-7-(3-trifluoromethyl-benzyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::CHEMBL354926

SMILES Nc1nc2c(Cc3cccc(c3)C(F)(F)F)c[nH]c2c(=O)[nH]1

InChI Key InChIKey=CBTABLJYKHBPFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50046232   

TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046232(2-Amino-7-(3-trifluoromethyl-benzyl)-3,5-dihydro-p...)
Affinity DataIC50:  190nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Bovine)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50046232(2-Amino-7-(3-trifluoromethyl-benzyl)-3,5-dihydro-p...)
Affinity DataIC50:  36nMAssay Description:Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed