BDBM50046360 CHEMBL104472::{1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester

SMILES CC(C)(C)OC(=O)N[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](C=O)CCCN=C(N)N

InChI Key InChIKey=YXBFBGUYNRARFM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50046360   

TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046360BDBM50046360({1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoy...)
Affinity DataIC50: 45nMAssay Description:Compound was tested in vitro for inhibitory activity against t-PA (tissue plasminogen activator)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046360BDBM50046360({1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoy...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046360BDBM50046360({1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoy...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046360BDBM50046360({1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoy...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Eli Lilly

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046360BDBM50046360({1-Benzyl-2-[2-(1-formyl-4-guanidino-butylcarbamoy...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed