BDBM50046762 7,8-Dihydroxy-isoquinoline-3-carboxylic acid amide::CHEMBL48384

SMILES NC(=O)c1cc2ccc(O)c(O)c2cn1

InChI Key InChIKey=FIBTUUYKTWYAAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046762   

TargetTyrosine-protein kinase Lck(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50046762(7,8-Dihydroxy-isoquinoline-3-carboxylic acid amide...)
Affinity DataIC50: 500nMAssay Description:Ability to inhibit autophosphorylation of immunopurified p56IckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
National Cancer Institute-Bethesda

Curated by ChEMBL
LigandPNGBDBM50046762(7,8-Dihydroxy-isoquinoline-3-carboxylic acid amide...)
Affinity DataIC50: 500nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50046762(7,8-Dihydroxy-isoquinoline-3-carboxylic acid amide...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article