BDBM50046871 CHEMBL3319254

SMILES O=C(Nc1cnc(Cl)c(Cl)c1)c1ccc2[nH]ncc2c1

InChI Key InChIKey=JLABGNSHSHVIHC-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50046871   

TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Ntz Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 27nMAssay Description:Inhibition of rat recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Ntz Lab

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50046871BDBM50046871(CHEMBL3319254)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat recombinant MAO-A expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed