BDBM50047309 CHEMBL3314576

SMILES CO[C@H]1CN(c2nc(-c3ncnn3C)c(C(=O)O)s2)CC[C@H]1NC(=O)c1[nH]c(C)c(Cl)c1Cl

InChI Key InChIKey=BMQFAHOPSKEIHS-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50047309   

TargetDNA gyrase subunit B(Staphylococcus aureus)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataIC50: 10nMAssay Description:Inhibition of ATPase activity of Staphylococcus aureus GyrBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetToxin ParE(Escherichia coli)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataIC50: 85nMAssay Description:Inhibition of ATPase activity of Escherichia coli ParEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Rat)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataEC50:  1.10E+5nMAssay Description:Stimulation of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataEC50:  1.40E+5nMAssay Description:Stimulation of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATPase activity of human MRP2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Rat)
AstraZeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50047309BDBM50047309(CHEMBL3314576)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of ATPase activity of rat Mrp2 assessed as inorganic phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMed